Which vaccination is contraindicated in pregnancy?

The correct choice pertains to live attenuated vaccines, such as the MMR (measles, mumps, and rubella) vaccine, which are contraindicated in pregnancy. Live attenuated vaccines contain a weakened form of the virus, which can pose risks to the developing fetus. In particular, rubella infection during pregnancy can result in serious congenital malformations known as congenital rubella syndrome. Therefore, it is crucial to avoid administering live attenuated vaccines to pregnant individuals to prevent possible adverse outcomes for the fetus.

In contrast, inactivated vaccines, like the flu vaccine, have been shown to be safe during pregnancy because they do not contain live pathogens and therefore cannot cause disease. Subunit vaccines, such as the HPV vaccine, similarly do not contain live components and are considered safe. mRNA vaccines, like those developed for COVID-19, have also been determined to be safe for pregnant individuals after thorough research and data collection on their effects during pregnancy.